Product Name: Thorase/Atad1
Product Number: AB-NN204-1
Size: 25 µg      Price:89.00
      $US
Target Full Name: ATPase family AAA domain-containing protein 1

Target Alias: ATAD1; AAA+ ATPase Thorase; Ab2-088; AFDC1; ATAD1_HUMAN; ATPase family; AAA domain containing 1; ATPase Thorase; AW107648; FLJ14600; FNP001; Thorase antibody

Product Type Specific: Thorase/Atad1 pan-specific antibody

Antibody Code: NN204-1

Antibody Target Type: Pan-specific

Protein UniProt: Q8NBU5

Protein SigNET: Q8NBU5

Antibody Type: Monoclonal

Antibody Host Species: Mouse

Antibody Ig Isotype Clone: IgG1

Antibody Immunogen Source: Fusion protein amino acids 1-361 (Full length) of mouse Thorase

Production Method: Protein G purified

Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.

Antibody Concentration: 1 mg/ml

Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide

Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.

Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence

Antibody Dilution Recommended: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Antibody Potency: Medium-high potency. Detects a ~40 kDa protein in cell and tissue lysates by Western blotting.

Antibody Species Reactivity: Human | Mouse | Rat

Antibody Positive Control: 1 µg/ml of SMC-347 was sufficient for detection of Thorase in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Antibody Specificity: Medium-low

Scientific Background: Thorase, also known as Atad1 or ATPase family AAA domain-containing protein 1 is involved in synaptic plasticity, learning and memory through the regulation of the surface expression of AMPA receptors (AMPAR). Thorase is widely expressed with the highest expression in the brain and testis.