Product Name: PHYH/PAHX
Product Number: AB-NN306-1
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Phytanoyl-CoA dioxygenase, peroxisomal
Target Alias: PAHX; peroxisomal; PhyH; PHYH1; Phytanic acid oxidase; phytanoil-CoA alpha hydroxylase; phytanoyl CoA 2 hydroxylase; Phytanoyl CoA 2 oxoglutarate dioxygenase; Phytanoyl CoA alpha hydroxylase; Phytanoyl CoA dioxygenase; Phytanoyl CoA dioxygenase peroxisomal; Phytanoyl-CoA alpha-hydroxylase; Phytanoyl-CoA dioxygenase; RD; LN1; LNAP1
Product Type Specific: PHYH/PAHX pan-specific antibody
Antibody Code: NN306-1
Antibody Target Type: Pan-specific
Protein UniProt: O14832
Protein SigNET: O14832
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Target Alias: PAHX; peroxisomal; PhyH; PHYH1; Phytanic acid oxidase; phytanoil-CoA alpha hydroxylase; phytanoyl CoA 2 hydroxylase; Phytanoyl CoA 2 oxoglutarate dioxygenase; Phytanoyl CoA alpha hydroxylase; Phytanoyl CoA dioxygenase; Phytanoyl CoA dioxygenase peroxisomal; Phytanoyl-CoA alpha-hydroxylase; Phytanoyl-CoA dioxygenase; RD; LN1; LNAP1
Product Type Specific: PHYH/PAHX pan-specific antibody
Antibody Code: NN306-1
Antibody Target Type: Pan-specific
Protein UniProt: O14832
Protein SigNET: O14832
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 1-338 (full-length) of human PhyH. Rat: 78% identity (264/338 amino acids identical). Mouse: 78% identity (264/338 amino acids identical).
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 50% glycerol, 0.1% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Antibody Immunogen Source: Fusion protein amino acids 1-338 (full-length) of human PhyH. Rat: 78% identity (264/338 amino acids identical). Mouse: 78% identity (264/338 amino acids identical).
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 50% glycerol, 0.1% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: In mouse brain lysates, this antibody detects a ~40 kDa protein by Western blotting.
Antibody Species Reactivity: Human | Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-472 was sufficient for detection of PHYH/PAHX in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: In mouse brain lysates, this antibody detects a ~40 kDa protein by Western blotting.
Antibody Species Reactivity: Human | Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-472 was sufficient for detection of PHYH/PAHX in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Scientific Background: Phytanoyl-CoA alpha-hydroxylase (PHYH) is also called Phytanoyl-CoA dioxygenase, peroxisomal, Phytanic acid oxidase and the gene names PHYH or PAHX. PAHX is involved in lipid metabolism and converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. PAHX is expressed in liver, kidney, and T-cells. Defects in PHYH can cause Refsum disease (RD).
© Kinexus Bioinformatics Corporation 2017