Product Name: REEP2
Product Number: AB-NN312-2
Size: 25 µg      Price:89.00
      $US
Target Full Name: Receptor expression-enhancing protein 2

Target Alias: C2orf19; SGC32445; LOC682105

Product Type Specific: REEP2 pan-specific antibody

Antibody Code: NN312-2

Antibody Target Type: Pan-specific

Protein UniProt: Q9BRK0

Protein SigNET: Q9BRK0

Antibody Type: Monoclonal

Antibody Host Species: Mouse

Antibody Ig Isotype Clone: IgG2A

Antibody Immunogen Source: Fusion protein amino acids 111-254 (cytoplasmic C-terminus) of mouse REEP2

Production Method: Protein G purified

Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.

Antibody Concentration: 1 mg/ml

Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.1% sodium azide

Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.

Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence

Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.

Antibody Potency: In mouse brain lysates, this antibody detects a ~30 kDa protein by Western blotting.

Antibody Species Reactivity: Mouse | Rat

Antibody Positive Control: A 1:100 dilution of SMC-481 was sufficient for detection of REEP2 in 20 µg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Antibody Specificity: Very high

Antibody Cross Reactivity: One weak ~75 kDa cross-reactive protein in mouse brain lysates.

Related Product 1: REEP1 pan-specific antibody (Cat. No.: AB-NN312-1)

Scientific Background: REEP2 belongs to the REEP family, which are transmembrane proteins that interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. REEP2 is also an integral membrane protein expressed in taste cells. Unlike its counterpart REEP1, REEP2 does not increase cell surface expression to sweet receptors, but instead alters their spatial organization (1).