Target Full Name: Prostaglandin G/H synthase 1

Target Alias: EC:1.14.99.1; PGHS1; PGHS-1; Prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PHS 1; EC 1.14.99.1; Prostaglandin-endoperoxide synthase 1; COX 3; PTGS1; PGH1_HUMAN; COX-1; PGG/HS; PTGHS; Cox3; PGH synthase 1; Cyclooxygenase-1; PHS1; Cyclooxygenase 1; Cyclooxygenase 3; included; Partial COX1 proteins; included; COX 1; COX1; PCOX1

Product Type Specific: COX1 pan-specific antibody

Antibody Code: NN381-1

Antibody Target Type: Pan-specific

Protein UniProt: P23219

Protein SigNET: P23219

Antibody Type: Polyclonal

Antibody Host Species: Rabbit

Antibody Immunogen Source: Synthetic peptide of Human Cyclooxygenase

Production Method: Peptide Affinity purified

Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.

Antibody Concentration: 1 mg/ml

Storage Buffer: Phosphate buffered saline, 50% glycerol, 0.09% sodium azide

Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.

Product Use: Western blotting

Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.

Antibody Potency: Detects a medium ~70 kDa protein band in mouse kidney, rat brain and HeLa cell lysates by Western blotting.

Antibody Species Reactivity: Human | Mouse | Rat

Antibody Positive Control: A 1:1000 dilution of SPC-707 was sufficient for detection of Cyclooxygenase in 15 µg of Human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Antibody Specificity: High

Antibody Cross Reactivity: No other prominent cross-reactive proteins in mouse and rat brain, and HeLa cell lysates, except for a ~22 kDa protein in mouse brain and a ~90KDa protein in HeLa cells.