Product Name: A2 (459-466)
Product Number: PE-01AET90
Size: 200 µg      Price:22.00
1 mg      $US45.00
Peptide Name: A2 (459-466)

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: SAINFEKL

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 920 Da

Peptide Purity Percent after Synthesis and Purification: >90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).
References

[1] Mareeva T, Lebedeva T, Anikeeva N, Manser T, Sykulev Y (2004) Antibody specific for the peptide.major histocompatibility complex. Is it T cell receptor-like? J Biol Chem 279: 44243–44249. doi:10.1074/jbc.M407021200. PMCID: PMC2570882

[2] Vasily Rybakin, Nicholas R. J. Gascoigne PLoS One. 2012; Negative Selection Assay Based on Stimulation of T Cell Receptor Transgenic Thymocytes with Peptide-MHC Tetramers 7(8): e43191; PMCID: PMC3416795; doi: 10.1371/journal.pone.0043191

[3] Jun Huang, Veronika I. Zarnitsyna, Baoyu Liu, Lindsay J. Edwards, Ning Jiang, Brian D. Evavold, Cheng Zhu; The kinetics of two dimensional TCR and pMHC interactions determine T cell responsiveness. Nature 2010 April 8; 464(7290): 932–936. PMID: 20357766; doi: 10.1038/nature08944