Product Name: GluR1 (850-862)
Product Number: PE-01AMJ95
Size: 200 µg      Price:42.00
1 mg      $US83.00
5 mg      182.00
Peptide Name: GluR1 (850-862)

Product Use: The peptide sequence is located in the C-terminus of the protein.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: INEAIRTSTLPRN

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1484.83 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: GluR1 is an ionotropic glutamate receptor. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel to genrate an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.