Peptide Name: OVA8 (258-265)

Product Use: This peptide belongs to the class of SIXNXEKX-peptides, where X designates randomised positions corresponding to major histocompatibility (MHC) class I anchor residues. It has been extensively used for studies of MHC class I binding.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Gallus gallus

Peptide Sequence: SIINFEKL

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 962.1 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

References

[1] Koch CP, Perna AM, Pillong M, Todoroff NK, Wrede P, Folkers G, Hiss JA, Schneider G. Scrutinizing MHC-I Binding Peptides and Their Limits of Variation. PLoS Comput Biol. 2013 Jun;9(6):e1003088. doi: 10.1371/journal.pcbi.1003088. PMID:23754940

[2] Lu X, Gibbs JS, Hickman HD, David A, Dolan BP, Jin Y, Kranz DM, Bennink JR, Yewdell JW, Varma R. Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15407-12. PMID: 22949678

[3] Denton AE, Wesselingh R, Gras S, Guillonneau C, Olson MR, Mintern JD, Zeng W, Jackson DC, Rossjohn J, Hodgkin PD, Doherty PC, Turner SJ. Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses. J Immunol. 2011 Dec 1;187(11):5733-44. doi: 10.4049/jimmunol.1003937. PMID: 22039305