Product Name: ESRRA (ERR1) (277-298)
Product Number: PE-01APL95
Size: 200 µg      Price:70.00
1 mg      $US141.00
5 mg      308.00
Peptide Name: ESRRA (ERR1) (277-298)

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: SLPLQDELAFAEDLVLDEEGAR

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Free carboxyl

Peptide Molecular Mass Calculated: 2430.58 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
References

[1] Sladek, R., Bader, J. A., & Giguere, V. (1997). The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Molecular and cellular biology, 17(9), 5400-5409; PMID:9271417