Product Name: Tyk2 (858-872)
Product Number: PE-01AVJ95
| Size: | 200 µg | Price: | 12.00 | |
| 1 mg | $US | 23.00 | ||
| 5 mg | 63.00 |
Peptide Name: Tyk2 (858-872)
Product Use: Services as a blocking peptide for use with the TYK2-1 rabbit polyclonal antibody (Cat. No.: AB-NK181-3) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSFRTILRDLTRLQPH
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1955.3 Da
Peptide Purity Percent after Synthesis and Purification: >50
Product Use: Services as a blocking peptide for use with the TYK2-1 rabbit polyclonal antibody (Cat. No.: AB-NK181-3) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSFRTILRDLTRLQPH
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1955.3 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Storage Stability: Tends to dimerize
Related Product 1: Tyk2 pan-specific antibody (Cat. No.: AB-NK181-3)
Peptide Form: Solid
Storage Conditions: -20°C
Storage Stability: Tends to dimerize
Related Product 1: Tyk2 pan-specific antibody (Cat. No.: AB-NK181-3)
Scientific Background: Tyk2 is a protein-tyrosine kinase of the TK group and JakA family. Phosphorylation of Y1054 and Y1055 increases phosphotransferase activity. Tyk2 mediates intracellular signal transduction from Type I interferon-alpha/beta receptor (IFN) signalling and phosphorylates the interferon-alpha/beta receptor alpha chain. Missense mutations in this gene have been found in colon and ovarian tumours.
© Kinexus Bioinformatics Corporation 2017