Product Name: Tyk2 (886-900)
Product Number: PE-01AVK99
Size: 200 µg      Price:12.00
1 mg      $US23.00
Peptide Name: Tyk2 (886-900)

Product Use: Services as a blocking peptide for use with the TYK2-2 rabbit polyclonal antibody (Cat. No.: AB-NK181-4) that is also available from Kinexus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CASDPTVFHKRYLKKI

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1905.3 Da

Peptide Purity Percent after Synthesis and Purification: >50

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Storage Stability: Tends to dimerize

Related Product 1: Tyk2 pan-specific antibody (Cat. No.: AB-NK181-4)

Scientific Background: Tyk2 is a protein-tyrosine kinase of the TK group and JakA family. Phosphorylation of Y1054 and Y1055 increases phosphotransferase activity. Tyk2 mediates intracellular signal transduction from Type I interferon-alpha/beta receptor (IFN) signalling and phosphorylates the interferon-alpha/beta receptor alpha chain. Missense mutations in this gene have been found in colon and ovarian tumours.