Product Name: Flt4 (227-241)
Product Number: PE-01AVP95
Size: 200 µg      Price:51.00
1 mg      $US102.00
5 mg      224.00
Peptide Name: Flt4 (227-241)

Product Use: Services as a blocking peptide for use with the VEGFR3 rabbit polyclonal antibody (Cat. No.: AB-NK064-2P) that is also available from Kinexus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CNELYDIQLLPRKSLE

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1933.2 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: Flt4 pan-specific antibody (Cat. No.: AB-NK064-2P)

Scientific Background: VEGFR3 (Flt4) is a protein-tyrosine kinase of the TK group and VEGFR family. It is a receptor for vascular endothelial growth factors (VEGF) C and D that is essential in angiogenesis and vasculogenesis. It is activated by binding VEGF-C and VEGF-D, which induce dimerization and autophosphorylation. VEGFR3 plays critical roles in some lymphangiogenetic mechanisms in cancer and metastasis. It is expressed in acute myeloid leukemia and other types of cancer, and are related to tumour angiogenesis and efficacy of traditional therapies.