Product Name: QSK (1249-1263)
Product Number: PE-01AYU85
Size: 200 µg      Price:38.00
1 mg      $US77.00
Peptide Name: QSK (1249-1263)

Product Use: Services as a blocking peptide for use with the SIK3-3 rabbit polyclonal antibody (Cat. No.: AB-NK250-3) that is also available from Kinexus. The peptide sequence is located in the C-terminus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CYKHPEVSFSMEQAGV

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Free carboxyl

Peptide Molecular Mass Calculated: 1812 Da

Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: QSK pan-specific antibody (Cat. No.: AB-NK250-3)

Scientific Background: SIK3 (QSK) is a protein-serine/threonine kinase of the CAMK group and CAMKL family. It is a member of the salt-inducible kinase family. SIK3 is activated by phosphorylation on T163 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39. It is a AMPK-family kinase that is ubiquitously expressed in the cytoplasm. In ovarian cancer, overexpression of SIK3 promotes G1/S cell cycle progression and cell proliferation and may therefore function as an oncoprotein.