Product Name: SHIP2 (477-491)
Product Number: PE-01BBS90
| Size: | 200 µg | Price: | 45.00 | |
| 1 mg | $US | 90.00 | ||
| 5 mg | 211.00 |
Peptide Name: SHIP2 (477-491)
Product Use: Services as a blocking peptide for use with the SHIP2-1 rabbit polyclonal antibody (Cat. No.: AB-NP045-1) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGDREWLDLLRGGLKE
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1859.1 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Product Use: Services as a blocking peptide for use with the SHIP2-1 rabbit polyclonal antibody (Cat. No.: AB-NP045-1) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGDREWLDLLRGGLKE
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1859.1 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: SHIP2 pan-specific antibody (Cat. No.: AB-NP045-1)
Storage Conditions: -20°C
Related Product 1: SHIP2 pan-specific antibody (Cat. No.: AB-NP045-1)
Scientific Background: SHIP2 (INPPL1) is a phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, and negatively regulate the PI3K (phosphoinositide 3-kinase) pathways. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signalling or GLUT4 trafficking. It confers resistance to dietary obesity. It may also hydrolyze PtdIns(1,3,4,5)P4.
© Kinexus Bioinformatics Corporation 2017