Product Name: FGFR4 (124-138)
Product Number: PE-01BBW99
| Size: | 200 µg | Price: | 51.00 | |
| 1 mg | $US | 102.00 | ||
| 5 mg | 224.00 |
Peptide Name: FGFR4 (124-138)
Product Use: Services as a blocking peptide for use with the FGFR4-4 rabbit polyclonal antibody (Cat. No.: AB-NK239-3) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSNDDEDPKSHRDPSN
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1814.8 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Product Use: Services as a blocking peptide for use with the FGFR4-4 rabbit polyclonal antibody (Cat. No.: AB-NK239-3) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSNDDEDPKSHRDPSN
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1814.8 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: FGFR4 pan-specific antibody (Cat. No.: AB-NK239-3)
Storage Conditions: -20°C
Related Product 1: FGFR4 pan-specific antibody (Cat. No.: AB-NK239-3)
Scientific Background: FGFR4 is a protein-tyrosine kinase of the TK group and FGFR family. It is a receptor kinase that is involved in recognizing fibroblast growth factors to control cell migration, differentiation, proliferation, and regulating lipid metabolism. It is activated by binding of fibroblast growth factor (FGF), which induces dimerization and autophosphorylation. Interaction with PLCG1 with FGFR4 is mediated through autophosphorylation of Y754. FGFR4 may be an oncoprotein (OP). Defects in FGFR4 have been linked to alveolar rhabdomyosarcomas (ARMS), breast fibroadenomas, gliomatosis cerebri, and anaplastic astrocytomas.
© Kinexus Bioinformatics Corporation 2017