Product Name: CDKL3 (505-523)
Product Number: PE-01BCO99
Size: | 200 µg | | Price: | 64.00 |
| 1 mg | | $US | 128.00 |
| 5 mg | | | 280.00 |
Peptide Name: CDKL3 (505-523)
Product Use: Services as a blocking peptide for use with the CDKL3-BCT rabbit polyclonal antibody (Cat. No.: AB-NK262-1) that is also available from Kinexus. The peptide sequence is located in the pre-C-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CANENKRKLNFSRSDRKEFH
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2478.7 Da
Peptide Purity Percent after Synthesis and Purification: >95
Scientific Background: CDKL3 (Cyclin-dependent kinase-like 3) is a protein-serine/threonine kinase of the CMGC group and CDKL family. It is likely that phosphorylation at T158 and Y160 is required for catalytic activity and phosphorylation at Y15 is inhibitory based on homology with other CDK's. It is an important regulator of cell cycle progression. The gene was found absent in leukemic and dysmyelopoiesis patients with chromosome 5q deletion.