Product Name: MLK4 (1018-1036)
Product Number: PE-01BEA90
| Size: | 200 µg | Price: | 56.00 | |
| 1 mg | $US | 112.00 |
Peptide Name: MLK4 (1018-1036)
Product Use: Services as a blocking peptide for use with the MLK4-CT rabbit polyclonal antibody (Cat. No.: AB-NK280-1) that is also available from Kinexus. The peptide sequence is located in the C-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CMRSKTSRPSIYELEKEFLS
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2403.8 Da
Peptide Purity Percent after Synthesis and Purification: >90
Product Use: Services as a blocking peptide for use with the MLK4-CT rabbit polyclonal antibody (Cat. No.: AB-NK280-1) that is also available from Kinexus. The peptide sequence is located in the C-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CMRSKTSRPSIYELEKEFLS
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2403.8 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MLK4 pan-specific antibody (Cat. No.: AB-NK280-1)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MLK4 pan-specific antibody (Cat. No.: AB-NK280-1)
Scientific Background: MLK4 (M3KL4) is a protein-serine/threonine kinase of the TKL group and MLK family. It acts to impair TLR4 signalling, and will not activate any of the JNK1/MAPK8, or p38/MAPK14, or ERK2/MAPK1 pathways. Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation. Mutations in MLK4 have been linked to Colorectal cancer (CRC).
© Kinexus Bioinformatics Corporation 2017