Product Name: MOK (388-407)
Product Number: PE-01BEC90
Size: 200 µg      Price:56.00
1 mg      $US112.00
5 mg      264.00
Peptide Name: MOK (388-407)

Product Use: Services as a blocking peptide for use with the MOK-CT rabbit polyclonal antibody (Cat. No.: AB-NK281-2) that is also available from Kinexus. The peptide sequence is located in the C-terminus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CIPASKKTDPQKDLKPAPQQ

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 2192.5 Da

Peptide Purity Percent after Synthesis and Purification: 90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: MOK pan-specific antibody (Cat. No.: AB-NK281-2)

Scientific Background: MOK is a protein-serine/threonine kinase of the CMGC group and RCK family. Phosphorylation appears to increase its enzymatic activity. MOK belongs to the MAP kinase superfamily, and it may phosphorylate exogenous substrates or autophosphorylate. The protein may functions in regulation of cillium length and intraflagellar transport in renal epithelial cells. MOK may be a tumour requiring protein (TRP), since it displays extremely low rates of mutation in human cancers. MOK is a renal tumour antigen that is silent in most normal tissues except for retina and a number of tumour cell types.