Product Name: CK1aSelectide
Product Number: PE-01BGU90
Size: | 200 µg | | Price: | 40.00 |
| 1 mg | | $US | 80.00 |
| 5 mg | | | 187.00 |
Peptide Name: CK1aSelectide
Product Use: For assaying the phosphotransferase activity of Casein kinase 1 - alpha1 (UniProt ID P48729).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KKDGEDDDSGAG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1367.6 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: CK1a
Scientific Background: CK1a1 is a protein-serine/threonine kinase in the CK1 group and CK1 family. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins, including CTNNB1 at S45, and PER1 and PER2. It appears to play a role in segregating chromosomes during mitosis and in keratin cytoskeleton disassembly, which regulate epithelial cell migration.