Product Name: CskSubtide
Product Number: PE-01BGY95
Size: 200 µg      Price:45.00
1 mg      $US91.00
5 mg      199.00
Peptide Name: CskSubtide

Product Use: For assaying the phosphotransferase activity of C-terminus of Src tyrosine kinase (UniProt ID P41240).

Peptide Production Method: Solid-phase peptide synthesis

Peptide Sequence: KKATEEQYQPGE

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Molecular Mass Calculated: 1581.67 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Peptide Recommended Enzyme: Csk

Scientific Background: CSK is a protein-tyrosine kinase of the TK group and Csk family. It is a protein kinase that can regulate cell differentiation, growth, and migration, along with mediating immune responses. A Y184F mutation leads to inhibited phosphorylation of CSK. Activity can be decreased by 2/3 with a Y304F mutation. PRKACA induced phosphorylation of CSK can be inhibited with a CSK mutation S364A.