Product Name: CskSubtide
Product Number: PE-01BGY95
Size: | 200 µg | | Price: | 45.00 |
| 1 mg | | $US | 91.00 |
| 5 mg | | | 199.00 |
Peptide Name: CskSubtide
Product Use: For assaying the phosphotransferase activity of C-terminus of Src tyrosine kinase (UniProt ID P41240).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KKATEEQYQPGE
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1581.67 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: Csk
Scientific Background: CSK is a protein-tyrosine kinase of the TK group and Csk family. It is a protein kinase that can regulate cell differentiation, growth, and migration, along with mediating immune responses. A Y184F mutation leads to inhibited phosphorylation of CSK. Activity can be decreased by 2/3 with a Y304F mutation. PRKACA induced phosphorylation of CSK can be inhibited with a CSK mutation S364A.