Product Name: DMPKSubtide
Product Number: PE-01BHC90
| Size: | 200 µg | Price: | 37.00 | |
| 1 mg | $US | 74.00 | ||
| 5 mg | 174.00 |
Peptide Name: DMPKSubtide
Product Use: For assaying the phosphotransferase activity of Myotonic dystrophy protein kinase (UniProt ID Q09013).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: RFRRKSFRRFG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1687.01 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Product Use: For assaying the phosphotransferase activity of Myotonic dystrophy protein kinase (UniProt ID Q09013).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: RFRRKSFRRFG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1687.01 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: DMPK
Peptide Recommended Enzyme: DMPK
Scientific Background: DMPK1 is a protein-serine/threonine kinase of the AGC group and DMPK family. It is a protein kinase that is essential for maintaining skeletal muscle structure and function. It is activated in response to G protein second messengers. Proteolytic processing of the C-terminus may remove the transmembrane domain and release the kinase from membranes stimulating its activity. Phosphorylation by Raf1 may result in activation of DMPK. It is maintained in an inactive conformation by the negative autoregulatory C-terminal coiled-coil region.
© Kinexus Bioinformatics Corporation 2017