Product Name: IKKSelectide
Product Number: PE-01BHN95
| Size: | 1 mg | Price: | 110.00 | |
| 5 mg | $US | 241.00 | ||
| 20 mg | 440.00 |
Peptide Name: IKKSelectide
Product Use: For assaying the phosphotransferase activity of Inhibitor of NF-kappa-B protein-serine kinase alpha (CHUK) (UniProt ID O15111).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KKGLDDGHDSGLDHG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1724.76 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Product Use: For assaying the phosphotransferase activity of Inhibitor of NF-kappa-B protein-serine kinase alpha (CHUK) (UniProt ID O15111).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KKGLDDGHDSGLDHG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1724.76 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: IKK
Peptide Recommended Enzyme: IKK
Scientific Background: IKKa (IKBKA, CHUK)) is a protein-serine/threonine kinase of the Other group and IKK family. It is involved in NF-kappa-B pathway, which activates multiple stress stimuli including inflammatory cytokines, infection, and DNA damage. The activity of the kinase enables for NF-kappa-B to enter the nucleus and stimulate the transcription of genes involved in the immune response, control of cell growth, and cellular protection against apoptosis. It is Inhibited by phosphorylation at S733, S740, and S750.
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