Product Name: Calmodulin (93-107) pY100
Product Number: PE-04AAH90
| Size: | 1 mg | Price: | 57.00 | |
| 5 mg | $US | 115.00 | ||
| 20 mg | 271.00 |
Peptide Name: Calmodulin (93-107) pY100
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Loop IV of CaM. Major site of phosphorylation. Probably inhibitory, since calmodulin phosphorylation by CK2a, likely at S102, is less able to activate the erythrocyte plasma membrane Ca2+ pump.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: FDKDGNR-pY-ISAAELR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Loop IV of CaM. Major site of phosphorylation. Probably inhibitory, since calmodulin phosphorylation by CK2a, likely at S102, is less able to activate the erythrocyte plasma membrane Ca2+ pump.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: FDKDGNR-pY-ISAAELR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1833.9 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins upon binding Ca2+. Several protein kinases and phosphatasees are among the many enzymes to be stimulated by the calmodulin-Ca2+ complex. Together with CCP110 and centrin, calmodulin is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
© Kinexus Bioinformatics Corporation 2017