Product Name: MERTK (747-754) pY749+pY753
Product Number: PE-04AAV85
| Size: | 200 µg | Price: | 56.00 | |
| 1 mg | $US | 111.00 | ||
| 5 mg | 241.00 |
Peptide Name: MERTK (747-754) pY749+pY753
Product Use: Services as a blocking peptide for use with the MERTK-pY749+pY753 rabbit polyclonal antibody (Cat. No.: AB-PK703) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. Y749 and Y753 phosphorylation stimulate phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KI-pY-SGD-pY-Y
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the MERTK-pY749+pY753 rabbit polyclonal antibody (Cat. No.: AB-PK703) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. Y749 and Y753 phosphorylation stimulate phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KI-pY-SGD-pY-Y
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1383.3 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MERTK - pY749+pY753 phosphosite-specific antibody (Cat. No.: AB-PK703)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1383.3 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MERTK - pY749+pY753 phosphosite-specific antibody (Cat. No.: AB-PK703)
Scientific Background: MERTK (Mer) is a protein-tyrosine kinase of the TK group and Axl family. It is a receptor kinase that functions in the regulation of cell survival, angiogenesis, migration and invasion, differentiation, and phagocytosis of apoptotic cells. Phosphorylation of Y749, Y753 and Y754 increases phosphotransferase activity.
© Kinexus Bioinformatics Corporation 2017