Product Name: CDK9 (188-194) pT191
Product Number: PE-04ABE85
Size: 200 µg      Price:32.00
1 mg      $US63.00
5 mg      137.00
Peptide Name: CDK9 (188-194) pT191

Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T191 phosphorylation is predicted to be inhibitory to phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: RVV-pT-LWY

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1231.3 Da

Peptide Purity Percent after Synthesis and Purification: >80

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: CDK9 is a protein-serine/threonine kinase of the CMGC group and CDK family. It is a protein kinase that is involved in chromatin binding and transcription regulator region DNA binding. Phosphorylation at S175 increases phosphotransferase activity.