Product Name: BARK1 (353-359) pY356
Product Number: PE-04ACJ85
| Size: | 200 µg | Price: | 35.00 | |
| 1 mg | $US | 71.00 | ||
| 5 mg | 153.00 |
Peptide Name: BARK1 (353-359) pY356
Product Use: Services as a blocking peptide for use with the BARK1-Y356 rabbit polyclonal antibody (Cat. No.: AB-PK537) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Y356 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: THG-pY-MAP
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the BARK1-Y356 rabbit polyclonal antibody (Cat. No.: AB-PK537) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Y356 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: THG-pY-MAP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1030.06 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: BARK1 - pY356 phosphosite-specific antibody (Cat. No.: AB-PK537)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1030.06 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: BARK1 - pY356 phosphosite-specific antibody (Cat. No.: AB-PK537)
Scientific Background: BARK1 (GRK2, ADRBK1) is a protein-serine/threonine kinase of the AGC group and GRK family. It is activated by G-beta/gamma subunit complex. Phosphorylation of S29 increases phosphotransferase activity. Phosphorylation of S670 inhibits G-beta/gamma-mediated activation of GRK2. Phosphorylation of Y13, Y86, Y92 and S685 increases interaction with G-alpha(q) and may induce protein degradation.
© Kinexus Bioinformatics Corporation 2017