Product Name: ENO2 (22-28) pY25
Product Number: PE-04ACT95
Size: 1 mg      Price:41.00
5 mg      $US82.00
20 mg      194.00
Peptide Name: ENO2 (22-28) pY25

Product Use: Services as a blocking peptide for use with the ENO2-pY25 rabbit polyclonal antibody (Cat. No.: AB-PN512) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Enolase_N domain. This is one of the major in vivo phosphorylation sites in ENO2. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: VDL-pY-TAK

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1063.09 Da

Peptide Purity Percent after Synthesis and Purification: >90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: ENO2 - pY25 phosphosite-specific antibody (Cat. No.: AB-PN512)

Scientific Background: ENO2 (gamma-enolase) catalyzes the biochemical reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O. This reaction is part of the metabolic pathway by which pyruvate is produced from D-glyceraldehyde 3 -phosphate. It also has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons.