Product Name: G6PD (398-404) pY401
Product Number: PE-04ACV80
Size: | 200 µg | | Price: | 35.00 |
| 1 mg | | $US | 71.00 |
| 5 mg | | | 153.00 |
Peptide Name: G6PD (398-404) pY401
Product Use: Services as a blocking peptide for use with the G6PD-pY401 rabbit polyclonal antibody (Cat. No.: AB-PN515) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the G6PD_C domain. One of the major in vivo phosphorylation sites in G6PD. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EAV-pY-TKM
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: G6PD catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a major route for the dissimilation of carbohydrates in addition to glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. The biochemical reaction catalyzed is: D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.