Product Name: Gab1 (403-409) pY406
Product Number: PE-04ACW80
Size: 200 µg      Price:11.00
1 mg      $US21.00
5 mg      58.00
Peptide Name: Gab1 (403-409) pY406

Product Use: Services as a blocking peptide for use with the Gab1-pY406 rabbit polyclonal antibody (Cat. No.: AB-PN516) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the mid-region of the protein. This is the second major in vivo phosphorylation site of Gab1. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: QDC-pY-DIP

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1107.08 Da

Peptide Purity Percent after Synthesis and Purification: >50

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: Gab1 - pY406 phosphosite-specific antibody (Cat. No.: AB-PN516)

Scientific Background: Gab1 is an adapter protein that plays a role in intracellular signalling cascades triggered by activated receptor-type kinases. It plays a role in FGFR1 signalling and is probably involved in signalling from the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).