Product Name: MAK (154-160) pT157
Product Number: PE-04ADW90
Size: 200 µg      Price:37.00
1 mg      $US74.00
5 mg      174.00
Peptide Name: MAK (154-160) pT157

Product Use: Services as a blocking peptide for use with the MAK-pT157 rabbit polyclonal antibody (Cat. No.: AB-PK689) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T157 phosphorylation stimulates phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: PPY-pT-DYV

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1107.11 Da

Peptide Purity Percent after Synthesis and Purification: >90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: MAK - pT157 phosphosite-specific antibody (Cat. No.: AB-PK689)

Scientific Background: MAK is a protein-serine/threonine kinase of the CMGC group and RCK family. It has been associated with maintaining ciliary length and modulating long-term photoreceptor cell survival. MAK has been shown to phosphorylate FZR1 during different stages of cell cycle. MAK may have a role in prostate cancer chromosome stability and in spermatogenesis.