Product Name: STAM2 (371-377) pY374
Product Number: PE-04AEF95
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: STAM2 (371-377) pY374

Product Use: Services as a blocking peptide for use with the STAM2-pY374 rabbit polyclonal antibody (Cat. No.: AB-PN538) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the C-terminal half of the protein. This is the second major in vivo phosphorylation site in STAM2. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: YSV-pY-SKL

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1112.18 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: STAM2 - pY374 phosphosite-specific antibody (Cat. No.: AB-PN538)

Scientific Background: STAM2 (STAMP2) is involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signalling leading to DNA synthesis and MYC induction. It may also play a role in T-cell development, and appears to be involved in down-regulation of receptor-tyrosine kinases via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex).