Product Name: SIT (87-93) pY90
Product Number: PE-04AEL99
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: SIT (87-93) pY90

Product Use: Services as a blocking peptide for use with the SIT-pY90 rabbit polyclonal antibody (Cat. No.: AB-PN535) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Sit domain. This is the major in vivo phosphorylation site of SIT. Phosphorylation induces interaction with Grb2.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: VPL-pY-GNL

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1028.11 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: SIT - pY90 phosphosite-specific antibody (Cat. No.: AB-PN535)

Scientific Background: SIT negatively regulates TCR (T-cell antigen receptor)-mediated signalling in T-cells. It is involved in positive selection of T-cells.