Product Name: CrkL (248-254) pY251
Product Number: PE-04AEQ95
| Size: | 200 µg | Price: | 47.00 | |
| 1 mg | $US | 94.00 | ||
| 5 mg | 206.00 |
Peptide Name: CrkL (248-254) pY251
Product Use: Services as a blocking peptide for use with the CrkL-pY251 rabbit polyclonal antibody (Cat. No.: AB-PN507) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the SH3_2 domain. The second major in vivo phosphoryation site in CrkL. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PCA-pY-DKT
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the CrkL-pY251 rabbit polyclonal antibody (Cat. No.: AB-PN507) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the SH3_2 domain. The second major in vivo phosphoryation site in CrkL. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PCA-pY-DKT
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1050.08 Da
Peptide Purity Percent after Synthesis and Purification: 95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CrkL - pY251 phosphosite-specific antibody (Cat. No.: AB-PN507)
Peptide Molecular Mass Calculated: 1050.08 Da
Peptide Purity Percent after Synthesis and Purification: 95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CrkL - pY251 phosphosite-specific antibody (Cat. No.: AB-PN507)
Scientific Background: CrkL is an adapter protein and phosphotyrosine-containing substrate implicated in transformation by Abl and in signalling by cytokines. When phosphorylated, Crkl binds through its Src homology 2 (SH2) domain to other tyrosine phosphoproteins such as paxillin and Cbl.
© Kinexus Bioinformatics Corporation 2017