Product Name: VIM (114-120) pY117
Product Number: PE-04AEW99
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: VIM (114-120) pY117

Product Use: Services as a blocking peptide for use with the VIM-pY117 rabbit polyclonal antibody (Cat. No.: AB-PN544) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal part of the Filament domain. One of the major in vivo phosphorylation sites in VIM. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: FAN-pY-IDK

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1123.16 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: VIM - pY117 phosphosite-specific antibody (Cat. No.: AB-PN544)

Scientific Background: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is found in the nucleus, endoplasmic reticulum, and mitochondria, attached either laterally or terminally. It is involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.