Product Name: VIM (114-120) pY117
Product Number: PE-04AEW99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: VIM (114-120) pY117
Product Use: Services as a blocking peptide for use with the VIM-pY117 rabbit polyclonal antibody (Cat. No.: AB-PN544) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal part of the Filament domain. One of the major in vivo phosphorylation sites in VIM. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: FAN-pY-IDK
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is found in the nucleus, endoplasmic reticulum, and mitochondria, attached either laterally or terminally. It is involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.