Product Name: snRNP70 (123-129) pY126
Product Number: PE-04AFF99
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: snRNP70 (123-129) pY126

Product Use: Services as a blocking peptide for use with the snRNP 70-pY126 rabbit polyclonal antibody (Cat. No.: AB-PN537) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the RRM_1 domain. This is the major in vivo phosphorylation site in snRNP70. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: FEV-pY-GPI

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1077.14 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: snRNP70 - pY126 phosphosite-specific antibody (Cat. No.: AB-PN537)

Scientific Background: SNRNP70 is part of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and spliceosome assembly. SNRNP70 binds to the loop I region of U1-snRNA.