Product Name: BRD2 (34-40) pS37
Product Number: PE-04AIU99
Size: 200 µg      Price:42.00
1 mg      $US84.00
5 mg      185.00
Peptide Name: BRD2 (34-40) pS37

Product Use: Services as a blocking peptide for use with the BRD2-pS37 rabbit polyclonal antibody (Cat. No.: AB-PK546) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located near the N-terminus of the protein. The effect of its phosphorylation is unclear. This is a major site of phosphorylation for BRD2.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: RKP-pS-LLY

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1129.27 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: BRD2 - pS37 phosphosite-specific antibody (Cat. No.: AB-PK546)

Scientific Background: BRD2 is a protein-serine/threonine kinase of the Atypical group and BRD family. It is a transcriptional regulator that associates with transcription complexes and acetylated chromatin during mitosis. It plays a role in regulation of transcription through chromatin remodeling and nucleosome assembly. Mutations on multiple sites on BRD2 lead to loss of homodimerization.