Product Name: CaMKK1 (71-77) pS74
Product Number: PE-04AJD99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: CaMKK1 (71-77) pS74
Product Use: Services as a blocking peptide for use with the CaMKK1-pS74 rabbit polyclonal antibody (Cat. No.: AB-PK557) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal quarter of the protein located before the kinase catalytic domain. On the This is the major in vivo phosphorylation sites in CaMMK1. S74 phosphorylation stimulates phosphotransferase activity and inhibits phosphotransferase activity by inducing binding to 14-3-3 eta.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RKL-pS-LQE
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the CaMKK1-pS74 rabbit polyclonal antibody (Cat. No.: AB-PK557) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal quarter of the protein located before the kinase catalytic domain. On the This is the major in vivo phosphorylation sites in CaMMK1. S74 phosphorylation stimulates phosphotransferase activity and inhibits phosphotransferase activity by inducing binding to 14-3-3 eta.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RKL-pS-LQE
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1126.22 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CaMKK1 - pS74 phosphosite-specific antibody (Cat. No.: AB-PK557)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1126.22 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CaMKK1 - pS74 phosphosite-specific antibody (Cat. No.: AB-PK557)
Scientific Background: CaMKK1 is a protein-serine/threonine kinase of the Other group and CAMKK family. It is a calcium/calmodulin-activated protein kinase that phosphorylates and activates CaMK1, CaMK1d, CaMK1g, CAMK4 and Akt1. Binding of calmodulin may releave intrasteric autoinhibition. It is partially inhibited upon phosphorylation by PRCAKA/PKA
© Kinexus Bioinformatics Corporation 2017