Product Name: DLK (266-272) pS269
Product Number: PE-04ALS85
Size: 200 µg      Price:32.00
1 mg      $US63.00
5 mg      137.00
Peptide Name: DLK (266-272) pS269

Product Use: Services as a blocking peptide for use with the DAPK -pS269 rabbit polyclonal antibody (Cat. No.: AB-PK590) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S269 phosphorylation is predicted to be stimulatory for phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: TKM-pS-FAG

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 995.06 Da

Peptide Purity Percent after Synthesis and Purification: >80

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: DLK - pS269 phosphosite-specific antibody (Cat. No.: AB-PK590)

Scientific Background: DLK (MAP3K12) is a protein-serine/threonine kinase of the TKL group and MLK family. It is a protein kinase that has been noted as a possible JNK/SAPK pathway activator. In vivo DLK has been noted to phosphorylate beta-casein, myelin basic protein, and histone 1.