Product Name: LMR2 (1447-1453) pS1450
Product Number: PE-04ANL95
Size: | 200 µg | | Price: | 42.00 |
| 1 mg | | $US | 84.00 |
| 5 mg | | | 185.00 |
Peptide Name: LMR2 (1447-1453) pS1450
Product Use: Services as a blocking peptide for use with the LMR2-pS1450 rabbit polyclonal antibody (Cat. No.: AB-PK684) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located near the C-terminus of the protein kinase. S1450 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KYF-pS-PPP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: LMR2 (LMTK2) is a protein-tyrosine kinase of the TK group and Lmr family. It is a receptor kinase that may have an essential role in spermatogenesis. In a large 2-stage genomewide association study of prostate cancer, SNP in intron of the LMR gene is associated susceptibility to prostate cancer. It has been shown to phosphorylate PPP1C, phosphorylase b and CFTR.