Peptide Name: 4E-BP1 (33-40) pT37+pT46

Product Use: Services as a blocking peptide for use with the 4E-BP1-pT37+pT46 rabbit polyclonal antibody (Cat. No.: AB-PN550) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the N-terminal portion of the translation regulatory protein. This is one of the major in vivo phosphorylation sites in 4E-BP1. T37 and T46 phosphorylation inhibits the inhibitory activity of 4E-BP1.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: DYST-pT-PGG

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1049.97 Da

Peptide Purity Percent after Synthesis and Purification: >90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: 4E-BP1 - pT37+pT46 phosphosite-specific antibody (Cat. No.: AB-PN550)