Product Name: ANXA1 (203-210) pY207
Product Number: PE-04ARB95
Size: 200 µg      Price:50.00
1 mg      $US100.00
5 mg      220.00
Peptide Name: ANXA1 (203-210) pY207

Product Use: Services as a blocking peptide for use with the ANXA1-pY207 rabbit polyclonal antibody (Cat. No.: AB-PN551) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the beginning of the third Annexin domain. The major in vivo phosphoryation site in Annexin A1. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: ARAL-pY-EAG

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1103.1 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: ANXA1 - pY207 phosphosite-specific antibody (Cat. No.: AB-PN551)

Scientific Background: Annexin A1 plays important roles in the innate immune response as effector of glucocorticoid-mediated responses such as down-regulation of the early phase of the inflammatory response and as a regulator of the inflammatory process by promoting resolution of inflammation and wound healing. It functions at least in part by activating the formyl peptide receptors and downstream signalling.