Product Name: DYRK4 (259-273) pY262+pT263+pY264+pS267+pY270
Product Number: PE-04ATD55
| Size: | 200 µg | Price: | 34.00 | |
| 1 mg | $US | 67.00 |
Peptide Name: DYRK4 (259-273) pY262+pT263+pY264+pS267+pY270
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Phosphorylation of Y262, T263 and Y264 is predicted to be stimulatory for phosphotransferase activity, whereas S267 and Y270 phosphorylation are predicted to be inhibitory.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QKV-pY-pT-pY-IQ-pS-RF-pY-RSP
Peptide Modifications N Terminus: Free amino
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Phosphorylation of Y262, T263 and Y264 is predicted to be stimulatory for phosphotransferase activity, whereas S267 and Y270 phosphorylation are predicted to be inhibitory.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QKV-pY-pT-pY-IQ-pS-RF-pY-RSP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2509.5 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 2509.5 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: DYRK4 is a protein-serine/threonine kinase of the CMGC group and DYRK family. It is a dual-specificity protein kinase that is suspected to play a role in spermiogenesis.
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