Product Name: ERK7 (172-179) pT175+pY177
Product Number: PE-04ATX01
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Peptide Name: ERK7 (172-179) pT175+pY177
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. Phosphorylation at T175 and Y177 are predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QAV(pT)E(pY)VA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. Phosphorylation at T175 and Y177 are predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QAV(pT)E(pY)VA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Modifications Other: Phosphorylated
Storage Conditions: -20°C
Scientific Background: ERK7 (MAPK15) is a protein-serine/threonine kinase of the CMGC group and MAPK family and Erk7 subgroup. It interacts with CSK/c-Src, ABL1, RET and TGFB1I1. Phosphorylation of T175 and Y177 increases the phosphotransferase activity of ERK7.
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