Target Full Name: MAPK/ERK protein-serine kinase 3 beta isoform (MKK3 beta); Dual specificity mitogen-activated protein kinase kinase 3

Target Alias: MAP kinase kinase 3; MAPK,ERK kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAP2K3; MP2K3; PRKMK3; P46734; ENSG00000034152

Product Type Specific: Protein kinase pan-specific antibody

Antibody Code: NK101-6

Antibody Target Type: Pan-specific

Protein UniProt: P46734

Protein SigNET: P46734

Antibody Type: Polyclonal

Antibody Host Species: Rabbit

Antibody Immunogen Source: Human MKK3 (MAP2K3, MEK3) sequence peptide Cat. No.: PE-01AWD99

Antibody Immunogen Sequence: CTDIAAFVKEILGEDS

Antibody Immunogen Description: Corresponds to amino acid residues T333 to S347; C-terminus

Production Method: The immunizing peptide was produced by solid phase synthesis on a multipep peptide synthesizer and purified by reverse-phase hplc chromatography. Purity was assessed by analytical hplc and the amino acid sequence confirmed by mass spectrometry analysis. This peptide was coupled to KLH prior to immunization into rabbits. New Zealand White rabbits were subcutaneously injected with KLH-coupled immunizing peptide every 4 weeks for 4 months. The sera from these animals was applied onto an agarose column to which the immunogen peptide was thio-linked. Antibody was eluted from the column with 0.1 M glycine, pH 2.5. Subsequently, the antibody solution was neutralized to pH 7.0 with saturated Tris.

Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.

Antibody Concentration: 0.75 mg/ml