Product Name: VGLUT3
Product Number: AB-NN362-1
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Vesicular glutamate transporter 3
Target Alias: DFNA25; deafness autosomal dominant 25; SLC17A8; Solute carrier family 17 member 8; VGLUT 3; Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8
Product Type Specific: Solute carrier protein pan-specific antibody
Antibody Code: NN362-1
Antibody Target Type: Pan-specific
Protein UniProt: Q8NDX2
Protein SigNET: Q8NDX2
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Target Alias: DFNA25; deafness autosomal dominant 25; SLC17A8; Solute carrier family 17 member 8; VGLUT 3; Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8
Product Type Specific: Solute carrier protein pan-specific antibody
Antibody Code: NN362-1
Antibody Target Type: Pan-specific
Protein UniProt: Q8NDX2
Protein SigNET: Q8NDX2
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 546-588 (cytoplasmic C-terminus) of rat VGlut3
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: In mouse brain lysates, this antibody detects a ~65 kDa protein by Western blotting.
Antibody Species Reactivity: Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-397 was sufficient for detection of VGLut3 in 20 µg of CV-1 fibroblast cells (lysate) transfected with VGlut3 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Related Product 1: VGLUT1 pan-specific antibody (Cat. No.: AB-NN361-1)
Related Product 2: VGLUT2 pan-specific antibody (Cat. No.: AB-NN323-1)
Antibody Potency: In mouse brain lysates, this antibody detects a ~65 kDa protein by Western blotting.
Antibody Species Reactivity: Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-397 was sufficient for detection of VGLut3 in 20 µg of CV-1 fibroblast cells (lysate) transfected with VGlut3 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Related Product 1: VGLUT1 pan-specific antibody (Cat. No.: AB-NN361-1)
Related Product 2: VGLUT2 pan-specific antibody (Cat. No.: AB-NN323-1)
Scientific Background: Vesicular Glutamate Transporter 3 (VGLUT3) is a multipass membrane protein restricted to synaptic vesicles of glutamergic neurons. It is specifically expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord, and thalamus. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.
References
[1] Amilhon B. et al. (2010) J Neurosci. 30(6): 2198-2210.
[2] Herzog E. et al. (2004) Neurosci. 123(4): 983-1002.
[1] Amilhon B. et al. (2010) J Neurosci. 30(6): 2198-2210.
[2] Herzog E. et al. (2004) Neurosci. 123(4): 983-1002.
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