Product Name: JNK2 (1-15)
Product Number: PE-01AXP90
| Size: | 200 µg | Price: | 45.00 | |
| 1 mg | $US | 90.00 | ||
| 5 mg | 211.00 |
Peptide Name: JNK2 (1-15)
Product Use: Services as a blocking peptide for use with the JNK2-3 rabbit polyclonal antibody (Cat. No.: AB-NK189-4) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MSDSKGDSQFYSVQVC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1779.93 Da
Peptide Purity Percent after Synthesis and Purification: >90
Product Use: Services as a blocking peptide for use with the JNK2-3 rabbit polyclonal antibody (Cat. No.: AB-NK189-4) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MSDSKGDSQFYSVQVC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1779.93 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: JNK2 pan-specific antibody (Cat. No.: AB-NK189-4)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: JNK2 pan-specific antibody (Cat. No.: AB-NK189-4)
Scientific Background: JNK2 (MAPK9) is a protein-serine/threonine kinase of the CMGC group and MAPK family. It is involved in the control of cell differentiation, transformation, migration, proliferation, and programmed cell death in response to stress and cytokines. It has also been implicated in preventing ubiquitination of p53.Phosphorylation of T183 and Y185 by either of two dual specificity kinases, MAP2K4 and MAP2K7, increases phosphotransferase activity. Phosphorylation of S129 also increases phosphotransferase activity. It is nhibited by dual specificity phosphatases, such as DUSP1, which target the T183 and Y185 activatory phosphorylation sites. JNK2 has been shown, in a cancer cell line to have a role in breast cancer cell motility.
© Kinexus Bioinformatics Corporation 2017