Product Name: IKKb (716-735)
Product Number: PE-01BDG99
Size: 200 µg      Price:64.00
1 mg      $US128.00
5 mg      280.00
Peptide Name: IKKb (716-735)

Product Use: Services as a blocking peptide for use with the IKKb-BCT rabbit polyclonal antibody (Cat. No.: AB-NK076-5) that is also available from Kinexus. The peptide sequence is located in the pre-C-terminus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CTLLENAIQDTVREQDQSFT

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 2310.5 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: IKKb pan-specific antibody (Cat. No.: AB-NK076-5)

Scientific Background: IKKb (IKBKB) is a protein-serine/threonine kinase of the Other group and IKK family. It functions in NF-kappa-B signalling and is activated by various indicators of cellular stress, including inflammatory cytokines, bacterial or viral products, and DNA damage. The activity of the kinase enables for NF-kappa-B to enter the nucleus and stimulate the transcription of genes involved in the immune response, control of cell growth, and cellular protection against apoptosis. IKKb may be a tumour requiring protein (TRP), since it displays extremely low rates of mutation in human cancers.