Product Name: MOK (287-303)
Product Number: PE-01BEB85
Size: | 1 mg | | Price: | 86.00 |
| 5 mg | | $US | 187.00 |
| 20 mg | | | 331.00 |
Peptide Name: MOK (287-303)
Product Use: Services as a blocking peptide for use with the MOK-AKCD rabbit polyclonal antibody (Cat. No.: AB-NK281-1) that is also available from Kinexus. The peptide sequence is located right after the kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EQRKTEKRALGSHRKAGC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2054.3 Da
Peptide Purity Percent after Synthesis and Purification: >80
Scientific Background: MOK is a protein-serine/threonine kinase of the CMGC group and RCK family. Phosphorylation appears to increase its enzymatic activity. MOK belongs to the MAP kinase superfamily, and it may phosphorylate exogenous substrates or autophosphorylate. The protein may functions in regulation of cillium length and intraflagellar transport in renal epithelial cells. MOK may be a tumour requiring protein (TRP), since it displays extremely low rates of mutation in human cancers. MOK is a renal tumour antigen that is silent in most normal tissues except for retina and a number of tumour cell types.