Product Name: ANXA2 (235-241) pY238
Product Number: PE-04ACI99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: ANXA2 (235-241) pY238
Product Use: Services as a blocking peptide for use with the ANXA2-pY238 rabbit polyclonal antibody (Cat. No.: AB-PN504) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the third Annexin domain. The second major in vivo phosphoryation site in Annexin A2. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: YSP-pY-DML
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: Annexin A2 is a calcium-regulated membrane-binding protein that binds two calcium ions with high affinity, which is greatly enhanced by anionic phospholipids. It may be involved in heat-stress response and inhibits PCSK9-enhanced LDL receptor degradation.