Product Name: ITSN2 (965-971) pY968
Product Number: PE-04ADA99
| Size: | 200 µg | Price: | 47.00 | |
| 1 mg | $US | 94.00 | ||
| 5 mg | 206.00 |
Peptide Name: ITSN2 (965-971) pY968
Product Use: Services as a blocking peptide for use with the ITSN2-pY968 rabbit polyclonal antibody (Cat. No.: AB-PN521) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the insert region that separates the SH3_2 and SH3_1 domains. This is the second major in vivo phosphorylation site in ITSN2. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EAL-pY-AAV
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the ITSN2-pY968 rabbit polyclonal antibody (Cat. No.: AB-PN521) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the insert region that separates the SH3_2 and SH3_1 domains. This is the second major in vivo phosphorylation site in ITSN2. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EAL-pY-AAV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 990.01 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: ITSN2 - pY968 phosphosite-specific antibody (Cat. No.: AB-PN521)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 990.01 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: ITSN2 - pY968 phosphosite-specific antibody (Cat. No.: AB-PN521)
Scientific Background: ITSN2 is an adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. It may regulate the formation of clathrin-coated vesicles (CCPs), and seems to be involved in CCPs maturation including invagination or budding. ITSN2 is involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). It also plays a role in dendrite formation by melanocytes.
© Kinexus Bioinformatics Corporation 2017