Product Name: DOK3 (395-401) pY398
Product Number: PE-04AHH99
Size: 200 µg      Price:47.00
1 mg      $US94.00
5 mg      206.00
Peptide Name: DOK3 (395-401) pY398

Product Use: Services as a blocking peptide for use with the Dok3-pY398 rabbit polyclonal antibody (Cat. No.: AB-PN508) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the last quarter of the protein. This is the major in vivo phosphorylation site in Dok3. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: EHL-pY-ENL

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1090.03 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: DOK3 - pY398 phosphosite-specific antibody (Cat. No.: AB-PN508)

Scientific Background: DOK3 is an adaptor or scaffolding protein that is a negative regulator of JNK signalling in B-cells through interaction with INPP5D/SHIP1.